The Blend of Ingredients
Celt Immuno-Care® is a blend of plant sterols with a unique broad spectrum antioxidant in the form of pine bark and an essential fatty acid complex (Cellasate™). Plant sterols, also known as phytosterols, are present in small amounts in all plants, including fruits and vegetables, seeds and legumes. It is difficult to get a sufficient amount in today’s diet, so supplementation is required.
They have unique biomedical effects on animals and humans. Celt Immuno-Care contains 300mg of plant sterols, the amount shown in research to be an optimum daily dose, and an essential part of the human diet.(1)
Rich in potent anti-oxidants, organic compounds and 100% natural, the proanthocyanidins and flavonoids, extracted from the bark of Radiata Pine trees, have been researched to help with heart health, allergies and many other health concerns. The powerful anti-oxidants may also help with anti- aging and DNA damage caused by free radicals.
These compounds consist of a highly active broad spectrum antioxidant mixture containing anti-inflammatory plant compounds, shown in studies to have many health supporting benefits. (2,3,4)
Cellasate™ is a proprietary patented blend of fruit and essential fatty acids sourced from selenium, flax seeds, bovine colostrum, bromelain, zinc and vitamin E. It is designed to increase the bioavailability and absorption of the nutrients contained in Celt Immuno-Care.
- The importance of sitosterol in human and animal nutrition. Pegel. S. African Jnl. Sc. 1997. Vol 93.
- Pilot study on the clinical effects of dietary supplementation with Enzogenol, a flavonoid extract of pine bark and vitamin C. Shand et al, Phytother. Res. 2003; 17:490-494.
- Comparison of antioxidant assays for flavonoid containing supplements. Free Gleseg S, Baird S. Rad Biol Med 1998; 25: S104.
- Extractives of Pinus Radiata bark. Phenolic components. Markham KR, Porter LJ NZ Jnl. Sci. 1973 Dec; 16(4): 751-761.
Phytosterols and T-helper Cell Balance
T-Helper cells are a very important part of the cell mediated response to disease and when the immune system is not in balance, we become subject to many of today’s diseases. T-cells are the cells that trigger immune cells to go on a “packman” like mission, to seek and destroy viruses, fungi, yeast, parasites, especially the ones that live inside cells. Like modern day scud missiles, they lock onto cells and destroy them.
Plant sterols have been shown to help balance the immune response, by enhancing T1- Helper cell proliferation and increasing the regulation of T2- Helper cells, to ultimately decrease conditions such as allergies, inflammation and may types of autoimmune conditions. (1,2,3).
- The Importance of Sitosterol in Human and Animal Nutrition. Pegel et al, S. African Jnl. Sc. 1997. Vol 93.
- Flow Cytometric Analysis of the Th1/Th2 Balance in Healthy Individuals. Breytenbach, Clark et al. Cell Biol. Int. 2001;25(1).
Effects of Increased Solar Radiation in HumanHealth. Longstreth, de Gruijl et al. United Nations Environmental Program. Ozone and Human Health Project.
Basophils produce histamine, which can lead to seasonal allergy symptoms like runny nose, itching eyes, sneezing and watery eyes.
A double blind, placebo-controlled clinical study conducted on the effects of Celt Immuno-Care® in allergic individuals, showed that over a 28 day period, users experienced a 96% decrease in basophils compared with 69% decrease in the control group.(1)
The release of histamine can also lead to asthma, due to its ability to constrict smooth muscle. The muscle around the airways in the lungs constricts, narrowing the airways and causing shortness of breath or even complete tracheal closure, a medical emergency.(2)
Flavanoids have also been shown to be effective at decreasing allergy symptoms, Celt Immuno-Care contains Enzogenol a powerful broad spectrum antioxidant rich in flavanoids. Enzogenol™ works synergistically with the plant sterols to accomplish the goal of symptom relief.(3)
- Pilot Clinical Trial on Celt Immuno-Care. Laidlaw M. Dept of Human Nutraceutical Res, University of Guelph, March 2005.
- The Role of Basophils in Allergic Disease. Knol, Mul et al ,Eur Respir Jnl Suppl. 1996 Aug. 22:126s-131s.
Flavonoids and Related Compounds as Anti–allergic substances. Kawai, Hirano et al, Allergol Int. 2007 June;56(2):113-23.
Fibromyalgia is thought to be a disease in which the immune system is chronically overactive. One of the main culprits is a pro- inflammatory cytokine IL-6, believed to be involved in the over activity of the immune system in people with fibromyalgia. Plant sterols have been shown to decrease IL-6 by approx 25%. (1)
Fibromyalgia has also been theorized to be partially due to an increase in free radicals, with fewer antioxidants and more oxidative damage being measured in people with fibromyalgia. Celt Immuno-Care® contains important antioxidants (Enzogenol™) capable of reducing free radicals that contribute to the development of muscle pain and fatigue disorders.(2,3)
- Pilot study conducted at the University of Guelph, by Human Nutraceutical Research Unit on the supplement Celt Immuno-Care. Laidlaw M. Pilot Clinical Trail, March 2005.
- Free radicals and antioxidants in primary fibromyalgia; An antioxidant stress disorder. Bagis S, Tamer L et al, Rheumatol Int. 2005 Apr;25 (3); 188-90.
- Effects of flavonoid extract Enzogenol with vit “C” on protein oxidation and DNA damage in older human subjects. Nutr Res. 2003;(23); 1199-1210.
Plant Sterols and Cholesterol
There is no doubt that much research now confirms that the consumption of plant sterols will beneficially effect cholesterol concentrations and reduce the negative effects on cardiovascular disease.
In a double blind study at the University of Guelph, Celt Immuno-Care® significantly reduced circulating levels of LDL-cholesterol (the bad cholesterol) and increased circulating levels of HDL-cholesterol (good cholesterol). There was a significant decrease in the ratio of TC/HDL and in the ratio of LDL/HDL cholesterol, which corresponds to a decrease in cardiovascular risk, as these ratios are markers for a reduction in the risk for developing atherosclerosis. (1,2,3)
Plant sterols are safe and easy to use, with no known side effects.
The effects of Celt Immuno-Care on blood lipid parameters in experimental and placebo groups from day 0 to day 28.
**statistically significant, p<0.05
- Pilot Clinical Trial on Celt Immuno-Care. Laidlaw M Dept Human. Nutraceutical Research, University of Guelph, March 2005.
- Plant Sterols and Stanols Lower LDL-cholesterol. Concentrations in Hypercholesterolemic Persons. Vanstone, Raeini-Sarjaz et al. An. Jnl. Nutr 2002 Dec:76(8).
Optimising the Effect of Plant Sterols on Cholesterol. Absorption in Man. Mattson Grundy et al, Am. Jnl. Clin. Nutr. 1082 Apr;35(4).
Chronic inflammation is involved in diseases as diverse as hardening of the arteries, heart valve dysfunction, obesity, diabetes, rheumatoid arthritis and others.
Whenever there is an increase in IL-6, there is trouble. There is good correlation between spiked levels of IL-6 and the conditions above.
Celt Immuno-Care® showed in a clinical trial a reduction in IL-6.
The other marker that affects disease is C-reactive protein, a molecule that is released in the blood in response to inflammation. This marker is now being used to determine the amount of inflammation in the body. It is being used in conjunction with other tests especially in determining the risk factors for CVD. Plant sterols have been shown to reduce CRP.
- Pilot Clinical Trial on Celt Immuno-Care. Laidlaw M. Dept Human Nutraceutical Research, University of Guelph, March 2005.
- C-Reactive Protein, Interleukin-6 as Predictors of Coronary Heart Disease.Tge Prime Study. Artt. Throm. Luc, Bard et al. Vasc Biol. 2003;23;1255.
- Direct Proinflammatory Effect of C-Reactive Protein on Human Endothelial Cells. Pasceri, Willerson et al. Circulation 2000:102:2165.
Relations of C-Reactive Protein and Interleukin-6 with Silent Brain Infarction. Hoshi, Kitagawa et al. Stroke 2005;36:768.
Prostate Enlargement (BPH)
Plant sterols and in particular betasitosterol, have been found in numerous studies to decrease symptoms of an enlarged prostate. Clinical studies show that betasitosterol, a major component in Celt Immuno-Care®, is one of the most effective plant-derived options available for BPH.
It can increase urinary flow, help prevent frequent bathroom visits.
Klippel. Double Blind clinical trial of beta sito sterol for BPH. BR.J.UROL.1997 sept 80 (3).